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1

Gene Therapy: Paving New Roads in the Treatment of Hemophilia

Yamaguti-Hayakawa, Gabriela, Ozelo, Margareth

Journal:

Seminars in Thrombosis and Hemostasis

Year:

2019

Language:

english

File:

PDF, 158 KB

english, 2019

2

Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response

Manno, Catherine S, Arruda, Valder R, Pierce, Glenn F, Glader, Bertil, Ragni, Margaret, Rasko, John, Ozelo, Margareth C, Hoots, Keith, Blatt, Philip, Konkle, Barbara

Journal:

Nature Medicine

Year:

2006

Language:

english

File:

PDF, 262 KB

english, 2006

3

VKORC1 V66M mutation in African Brazilian patients resistant to oral anticoagulant therapy

Fernanda A. Orsi, Joyce M. Annichino Bizzacchi, Erich V. de Paula, Margareth C. Ozelo, Michael R. Langley, Karen E. Weck

Journal:

Thrombosis Research

Year:

2010

Language:

english

File:

PDF, 175 KB

english, 2010

4

DOENÇA DE VON WILLEBRAND SECUNDÁRIA AO LÚPUS ERITEMATOSO SISTÊMICO: RELATO DE DOIS CASOS

Cortês, M.M.M., Pignatari, J.F., Barboza, F.F., Sodré, A.C.M., Appenzeller, S., Sachetto, Z., Costallat, L.T.L., Ozelo, M.C., Pugliesi, A.A.V.

Journal:

Revista Brasileira de Reumatologia

Year:

2017

File:

PDF, 60 KB

2017

5

MSM photodetector with an integrated microlens array for improved optical coupling

H. F. B. Ozelo, L. E. M. De Barros Jr., B. Nabet, L. G. Neto, M. A. Romero, A. C. S. Ramos, J. W. Swart

Journal:

Microwave and Optical Technology Letters

Year:

2000

Language:

english

File:

PDF, 238 KB

english, 2000

6

Genetic variability of platelet glycoprotein Ibα gene

Margareth C. Ozelo, Devanira S.P. Costa, Lucia H. Siqueira, Tania M.F. Machado, Vagner Castro, Marilda S. Gonçalves, Raimundo C. Menezes, Manoel Soares, Joyce M. Annichino-Bizzacchi, Fernando F. Costa

Journal:

American Journal of Hematology

Year:

2004

Language:

english

File:

PDF, 286 KB

english, 2004

7

Polymorphisms of methylenetetrahydrofolate reductase (MTHFR), methionine synthase (MTR), methionine synthase reductase (MTRR), and thymidylate synthase (TYMS) in multiple myeloma risk

Carmen S.P. Lima, Manoela M. Ortega, Margareth C. Ozelo, Renato C. Araujo, Cármino A. De Souza, Irene Lorand-Metze, Joyce M. Annichino-Bizzacchi, Fernando F. Costa

Journal:

Leukemia Research

Year:

2008

Language:

english

File:

PDF, 133 KB

english, 2008

8

Use of recombinant factor VIIa in the management of severe bleeding episodes in patients with Bernard–Soulier syndrome

Margareth Castro Ozelo, Pavel Svirin, Lubov Larina

Journal:

Annals of Hematology

Year:

2005

Language:

english

File:

PDF, 126 KB

english, 2005

9

What is a cure and how do we get there?

M. W. Skinner, D. P. Lillicrap, J. McMillan, M. Castro Ozelo, G. F. Pierce

Journal:

Year:

2004

Language:

english

File:

PDF, 54 KB

english, 2004

10

A cost evaluation of treatment alternatives for mild-to-moderate bleeding episodes in patients with haemophilia and inhibitors in Brazil

M. C OZELO, P. R VILLAÇA, J. O. S. C DE ALMEIDA, T. M. F BUENO, P. A. P DE MIRANDA, W. M HART, M KARAMALIS

Journal:

Year:

2007

Language:

english

File:

PDF, 635 KB

english, 2007

11

Unique strategies for therapeutic gene transfer in haemophilia A and haemophilia B

R. R. MONTGOMERY, P. E. MONAHAN, M. C. OZELO

Journal:

Year:

2010

Language:

english

File:

PDF, 71 KB

english, 2010

12

Evaluation of the host response to endotoxemia of FVIII and FIX deficient mice

S. M. C. VANCINE, S. K. PICOLI-QUAINO, D. S. P. COSTA, S. A. L. MONTALVAO, M. C. OZELO, J. M. ANNICHINO-BIZZACCHI, E. V. DE PAULA

Journal:

Year:

2011

Language:

english

File:

PDF, 441 KB

english, 2011

13

Non-operative management of blunt major hepatic injury in a young adult with severe haemophilia A

B. M. T. PEREIRA, G. P. FRAGA, E. S. HIRANO, C. V. CARMONA, M. C. OZELO

Journal:

Year:

2012

Language:

english

File:

PDF, 112 KB

english, 2012

14

Rapid detection of the prothrombin C20209T variant by differential sensitivity to restriction endonuclease digestion

M. C. Ozelo, J. M. Annichino-Bizzacchi, E. S. Pollak, J. E. Russell

Journal:

Journal of Thrombosis and Haemostasis

Year:

2003

Language:

english

File:

PDF, 273 KB

english, 2003

15

Reduction of the immune response to factor VIII mediated through tolerogenic factor VIII presentation by immature dendritic cells

M. QADURA, M. OTHMAN, B. WATERS, R. CHEGENI, K. WALKER, A. LABELLE, M. OZELO, C. HOUGH, D. LILLICRAP

Journal:

Journal of Thrombosis and Haemostasis

Year:

2008

Language:

english

File:

PDF, 337 KB

english, 2008

16

An inherited mutation leading to production of only the short isoform of GATA-1 is associated with impaired erythropoiesis

Hollanda, Luciana M, Lima, Carmen S P, Cunha, Anderson F, Albuquerque, Dulcinéia M, Vassallo, José, Ozelo, Margareth C, Joazeiro, Paulo P, Saad, Sara T O, Costa, Fernando F

Journal:

Nature Genetics

Year:

2006

Language:

english

File:

PDF, 507 KB

english, 2006

17

CORRIGENDUM: Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response

Manno, C S, Arruda, V R, Pierce, G F, Glader, B, Ragni, M, Rasko, J, Ozelo, M C, Hoots, K, Blatt, P, Konkle, B

Journal:

Nature Medicine

Year:

2006

Language:

english

File:

PDF, 53 KB

english, 2006

18

Brain plasticity for verbal and visual memories in patients with mesial temporal lobe epilepsy and hippocampal sclerosis: An fMRI study

Andréa Alessio, Fabricio R.S. Pereira, Maurício S. Sercheli, Jane M. Rondina, Helka B. Ozelo, Elisabeth Bilevicius, Tatiane Pedro, Roberto J.M. Covolan, Benito P. Damasceno, Fernando Cendes

Journal:

Human Brain Mapping

Year:

2012

Language:

english

File:

PDF, 764 KB

english, 2012

19

Clinical Impact of Oral Health Indexes in Dental Extraction of Hemophilic Patients

Maria Elvira P. Correa, Joyce M. Annicchino-Bizzacchi, Jacks Jorge Jr, Oslei Paes de Almeida, Margareth C. Ozelo, Francisco José P. Aranha, Maria Lourdes Barjas-Castro

Journal:

Journal of Oral and Maxillofacial Surgery

Year:

2006

Language:

english

File:

PDF, 77 KB

english, 2006

20

82 Megakaryopoiesis in myelodysplastic syndromes: Morphological and immunocytochemical features

I. Lorand-Metze, G.B. Oliveira, M.C. Ozelo

Journal:

Leukemia Research

Year:

1997

Language:

english

File:

PDF, 144 KB

english, 1997

21

Meeting the challenges of haemophilia care and patient support in China and Brazil

MARGARETH C. OZELO, MÁRCIA A. P. MATTA, RENCHI YANG

Journal:

Year:

2012

Language:

english

File:

PDF, 68 KB

english, 2012

22

Asymmetrical hippocampal connectivity in mesial temporal lobe epilepsy: evidence from resting state fMRI

Fabrício RS Pereira, Andréa Alessio, Maurício S Sercheli, Tatiane Pedro, Elizabeth Bilevicius, Jane M Rondina, Helka FB Ozelo, Gabriela Castellano, Roberto JM Covolan, Benito P Damasceno, Fernando Cen

Journal:

BMC Neuroscience

Year:

2010

Language:

english

File:

PDF, 3.19 MB

english, 2010

23

Association between estrogen receptor alpha and beta gene polymorphisms and deep vein thrombosis

Aline Morandi Aléssio, Nelci Fenalti Höehr, Lúcia Helena Siqueira, Margareth Castro Ozelo, Antônio de Pádua Mansur, Joyce Maria Annichino-Bizzacchi

Journal:

Thrombosis Research

Year:

2007

Language:

english

File:

PDF, 135 KB

english, 2007

24

Simultaneous bleeding and thrombosis in superwarfarin poisoning

Erich Vinicius De Paula, Silmara Aparecida Lima Montalvao, Paulo Roberto Madureira, Ronan Jose Vieira, Joyce Maria Annichino-Bizzacchi, Margareth Castro Ozelo

Journal:

Thrombosis Research

Year:

2009

Language:

english

File:

PDF, 224 KB

english, 2009

25

Effects of high platelet concentration in collecting and freezing dry platelets concentrates

Evaldo Pasquini Landi, Eduardo Gasparotto Roveri, Margareth Castro Ozelo, Joyce Maria Annichino-Bizzacchi, Andreia Fernanda Origa, Aparecida Ribeiro de Carvalho Reis, Cármino Antonio de Souza, José Fr

Journal:

Transfusion and Apheresis Science

Year:

2004

Language:

english

File:

PDF, 266 KB

english, 2004

26

Factor VIII inhibitors in patients with congenital severe haemophilia A and its relation to genotype

S. F. Pio, M. C. Ozelo, A. dos Santos, B. V. de carvalho, C. Caram, D. Zouain, G. C. Oliveira, S. M. Rezende

Journal:

Year:

2012

Language:

english

File:

PDF, 109 KB

english, 2012

27

Visual memory encoding and retrieval in patients with unilateral mesial temporal lobe epilepsy: a fMRI study

A Alessio, JM Rondina, MS Sercheli, F Pereira, H Ozelo, E Bilevicius, T Pedro, M Zibetti, RJM Covolan, BP Damasceno, F Cendes

Journal:

Year:

2009

Language:

english

File:

PDF, 121 KB

english, 2009

28

Engagement of anatomical regions in a visual memory task in patients with temporal lobe epilepsy - a fMRI ROI analysis

JM Rondina, A Alessio, MS Sercheli, F Pereira, H Ozelo, E Bilevicius, T Pedro, M Zibetti, RJM Covolan, BP Damasceno, F Cendes

Journal:

Year:

2009

Language:

english

File:

PDF, 126 KB

english, 2009

29

Effective connectivity of unilateral left or right mesial temporal lobe epilepsy during verbal memory task

FRS Pereira, A Alessio, JM Rondina, T Pedro, MS Sercheli, HFB Ozelo, E Bilevicius, MVW Zibetti, G Castellano, RJM Covolan, BP Damasceno, F Cendes

Journal:

Year:

2009

Language:

english

File:

PDF, 126 KB

english, 2009

30

Results from a large multinational clinical trial (guardian™3) using prophylactic treatment with turoctocog alfa in paediatric patients with severe haemophilia A: safety, efficacy and pharmacokinetics

Kulkarni, R., Karim, F. A., Glamocanin, S., Janic, D., Vdovin, V., Ozelo, M., Rageliene, L., Carboni, E., Laguna, P., Dobaczewski, G., Seremetis, S., Lindblom, A., Santagostino, E.

Journal:

Year:

2013

Language:

english

File:

PDF, 175 KB

english, 2013

31

Surgery in patients with hemophilia: Is thromboprophylaxis mandatory?

Ozelo, Margareth C.

Journal:

Thrombosis Research

Year:

2012

Language:

english

File:

PDF, 144 KB

english, 2012

32

Results from a large multinational clinical trial (guardian™1) using prophylactic treatment with turoctocog alfa in adolescent and adult patients with severe haemophilia A: safety and efficacy

Lentz, S. R., Misgav, M., Ozelo, M., Šalek, S. Z., Veljkovic, D., Recht, M., Cerqueira, M., Tiede, A., Brand, B., Mancuso, M. E., Seremetis, S., Lindblom, A., Martinowitz, U.

Journal:

Year:

2013

Language:

english

File:

PDF, 214 KB

english, 2013

33

Increased adhesive and inflammatory properties in blood outgrowth endothelial cells from sickle cell anemia patients

Sakamoto, Tatiana Mary, Lanaro, Carolina, Ozelo, Margareth Castro, Garrido, Vanessa Tonin, Olalla-Saad, Sara Teresinha, Conran, Nicola, Costa, Fernando Ferreira

Journal:

Microvascular Research

Year:

2013

Language:

english

File:

PDF, 644 KB

english, 2013

34

Spatial distribution of BOLD responses in mesial temporal lobe epilepsy: an EEG-fMRI study

Sercheli, MS, Bilevicius, E, Ozelo, H, Alessio, A, Pereira, FRS, Rondina, JM, Pedro, T, Cendes, F, Covolan, RJM

Journal:

Year:

2009

Language:

english

File:

PDF, 122 KB

english, 2009

35

Correlation between EEG theta and alpha oscillations and BOLD response during a working memory study

Ozelo, HFB, Alessio, A, Sercheli, MS, Bilevicius, E, Pedro, T, Damasceno, BP, Cendes, F, Covolan, RJM

Journal:

Year:

2009

Language:

english

File:

PDF, 140 KB

english, 2009

36

Pattern changes of EEG oscillations and BOLD signals associated with temporal lobe epilepsy as revealed by a working memory task

Ozelo, Helka FB, Alessio, Andréa, Sercheli, Maurício S, Bilevicius, Elizabeth, Pedro, Tatiane, Pereira, Fabrício RS, Rondina, Jane M, Damasceno, Benito P, Cendes, Fernando, Covolan, Roberto JM

Journal:

BMC Neuroscience

Year:

2014

Language:

english

File:

PDF, 887 KB

english, 2014

37

Evidence of Multiyear Factor IX Expression by AAV-Mediated Gene Transfer to Skeletal Muscle in an Individual with Severe Hemophilia B

JIANG, H, PIERCE, G, OZELO, M, DEPAULA, E, VARGAS, J, SMITH, P, SOMMER, J, LUK, A, MANNO, C, HIGH, K

Journal:

Molecular Therapy

Year:

2006

Language:

english

File:

PDF, 242 KB

english, 2006

38

A novel use of thromboelastography in type 2B von Willebrand disease

Toukh, M., Ozelo, M. C., Angelillo-Scherrer, A., Othman, M.

Journal:

Clinical and Laboratory Haematology

Year:

2013

Language:

english

File:

PDF, 235 KB

english, 2013

39

Efficacy and safety of dapsone as a second-line treatment in non-splenectomized adults with immune thrombocytopenic purpura

Vancine-Califani, Suley Mara Chaddad, De Paula, Erich Vinicius, Ozelo, Margareth Castro, Orsi, Fernanda Loureiro Andrade, Fabri, Daniela Ramos, Annichino-Bizzacchi, Joyce Maria

Journal:

Year:

2008

Language:

english

File:

PDF, 218 KB

english, 2008

40

Phase 3 Study of Recombinant Factor IX Fc Fusion Protein in Hemophilia B

Powell, Jerry S., Pasi, K. John, Ragni, Margaret V., Ozelo, Margareth C., Valentino, Leonard A., Mahlangu, Johnny N., Josephson, Neil C., Perry, David, Manco-Johnson, Marilyn J., Apte, Shashikant, Bak

Journal:

New England Journal of Medicine

Year:

2013

Language:

english

File:

PDF, 623 KB

english, 2013

41

[IEEE 1999 SBMO/IEEE MTT-S International Microwave and Optoelectronics Conference - Rio de Janeiro, Brazil (9-12 Aug. 1999)] 1999 SBMO/IEEE MTT-S International Microwave and Optoelectronics Conference - MSM photodetector with an integrated microlens array for improved optical coupling

Ozelo, H.F.B., de Barros, L.E.M., Nabet, B., Neto, L.G., Romero, M.A., Swart, J.W.

Year:

1999

Language:

english

File:

PDF, 442 KB

english, 1999

42

Establishing a harmonized haemophilia registry for countries with developing health care systems

Alzoebie, A., Belhani, M., Eshghi, P., Kupesiz, A. O., Ozelo, M., Pompa, M. T., Potgieter, J., Smith, M.

Journal:

Year:

2013

Language:

english

File:

PDF, 102 KB

english, 2013

43

Safety and efficacy of cryoprecipitate-poor plasma as a replacement fluid for therapeutic plasma exchange in thrombotic thrombocytopenic purpura: A single center retrospective evaluation

Stefanello, Bianca, De Paula, Erich Vinícius, Andrade Orsi, Fernanda, Comenalli Marques, Jose Francisco, Gasparotto Roveri, Eduardo, Pereira Colella, Marina, Castro Ozelo, Margareth, Maria Annichino-B

Journal:

Journal of Clinical Apheresis

Year:

2014

Language:

english

File:

PDF, 95 KB

english, 2014

44

Musculoskeletal evaluation in severe haemophilia A patients from Latin America

Ozelo, M. C., Villaça, P. R., Pérez-Bianco, R., Candela, M., Garcia-Chavez, J., Moreno-Rodriguez, B., Rodrigues, M. B., Rodriguez-Grecco, I., Solano, M. H., Chumpitaz, G., Morales-Gana, M. M., Ruiz-Sá

Journal:

Year:

2014

Language:

english

File:

PDF, 223 KB

english, 2014

45

Long-acting recombinant factor IX Fc fusion protein (rFIXFc) for perioperative management of subjects with haemophilia B in the phase 3 B-LONG study

Powell, Jerry S., Apte, Shashikant, Chambost, Hervé, Hermans, Cedric, Jackson, Shannon, Josephson, Neil C., Mahlangu, Johnny N., Ozelo, Margareth C., Peerlinck, Kathelijne, Pasi, John, Perry, David, R

Journal:

British Journal of Haematology

Year:

2015

Language:

english

File:

PDF, 218 KB

english, 2015

46

Systematic Analysis of Bleeding Phenotype in PT-VWD Compared to Type 2B VWD Using an Electronic Bleeding Questionnaire

Kaur, H., Ozelo, M., Scovil, S., James, P. D., Othman, M.

Journal:

Clinical and Applied Thrombosis/Hemostasis

Year:

2014

Language:

english

File:

PDF, 180 KB

english, 2014

47

A longitudinal evaluation of anti-FVIII antibodies demonstrated IgG4 subclass is mainly correlated with high-titre inhibitor in haemophilia A patients

Montalvão, S. A. L., Tucunduva, A. C., Siqueira, L. H., Sambo, A. L. A., Medina, S. S., Ozelo, M. C.

Journal:

Year:

2015

Language:

english

File:

PDF, 239 KB

english, 2015

48

Possible Association between Cytomegalovirus Infection and Gastrointestinal Bleeding in Hemophiliac Patients

Nogueira, Eliana, Arruda, Valder R., Annicchino Bizzacchi, Joyce M., Costa, Fernando F., Castro Ozelo, Margareth, L&uacute, cio Rossi, Claudio, Costa, Sandra C.B.

Journal:

Acta Haematologica

Year:

2000

Language:

english

File:

PDF, 287 KB

english, 2000

49

Recombinant activated factor VII in the treatment of bleeds and for the prevention of surgery-related bleeding in congenital haemophilia with inhibitors

Santagostino, Elena, Escobar, Miguel, Ozelo, Margareth, Solimeno, Luigi, Arkhammar, Per, Lee, Hye Youn, Rosu, Gabriela, Giangrande, Paul

Journal:

Year:

2015

Language:

english

File:

PDF, 215 KB

english, 2015

50

Switching to recombinant factor IX Fc fusion protein prophylaxis results in fewer infusions, decreased factor IX consumption and lower bleeding rates

Powell, Jerry, Shapiro, Amy, Ragni, Margaret, Negrier, Claude, Windyga, Jerzy, Ozelo, Margareth, Pasi, John, Baker, Ross, Potts, James, Li, Shuanglian, Mei, Baisong, Pierce, Glenn F., Robinson, Brian

Journal:

British Journal of Haematology

Year:

2015

Language:

english

File:

PDF, 589 KB

english, 2015